Maantibayotiki ndi mtundu wa mankhwala omwe amagwiritsidwa ntchito pochiza ndi kupewa matenda a bakiteriya.Akhoza kupha kapena kulepheretsa kukula kwa mabakiteriya.
Cholinga chosefera:
Zosefera: Chotsani tinthu tating'onoting'ono, colloid, ndikukulitsa moyo wantchito wazosefera zabwino zomwe zimatsatiridwa.
Fyuluta yabwino: chotsani mabakiteriya, mycoplasma.
Zosefera:
1. Chotsani particles, colloid, mabakiteriya, mycoplasma.
2. Kutuluka kwaulele kudzera muzosakaniza zomwe zili muzomangamanga (makamaka zogwirizana ndi mankhwala.)
3. Khola kusefera otaya.
Zosankha zosefera:
| Njira yosefera | Zosankha zosefera |
| Zosefera | GF |
| Mphepo | IPF |
| Wosabala | IPS |
Njira Yosefera:
LVP ndi madzi a jekeseni wosabala m'thupi la munthu ndi mtsempha, ndipo kuchuluka kwake sikuchepera 50ml.
Chofunikira chachikulu cha LVP:
Madzi, shuga, amino acid, mchere, ndi viscous michere yankho.
Tsopano zomwe zikupezeka pamsika makamaka ndi mitundu inayi ya LVP:
Glucose, NaCl, Glucose/NaCl, Metronidazole
Cholinga chosefera:
Zosefera: Chotsani tinthu tating'onoting'ono, colloid, ndikukulitsa moyo wantchito wazosefera zabwino zomwe zimatsatiridwa.
Fyuluta yabwino: chotsani katundu wochepa wachilengedwe;kusefera wosabala
Zosefera:
Chitetezo: Zosefera ziyenera kukhala zamphamvu zamakina, monga kuyika mabotolo pansi pa kuthamanga kwambiri komanso kuthamanga kwambiri
Kukhazikika: Zosefera ziyenera kupereka liwiro lokhazikika la kusefera komanso kusefera bwino
Zopanda mabakiteriya: Palibe mabakiteriya amoyo mu LVP
Zosefera Kachitidwe:
Chithunzi cha Makina Osefera:
Small volume parenterals (SVP) imaphatikizapo mankhwala osiyanasiyana achikhalidwe komanso opangidwa ndi bioengineered.Mankhwalawa nthawi zambiri amaikidwa m'matumba ang'onoang'ono (osakwana 20 ml), ma syringe odzazidwa ndi ma ampoules, kapena amapangidwa mu ufa wa lyophilized.Ma SVP ambiri amafunikira kukonzedwa kwa aseptic chifukwa chosowa kukhazikika kwa kutentha.
Kusefera koyezera kumagwiritsidwa ntchito pambuyo pa kaphatikizidwe kapena musanadzaze.Ndipo imatha kuwonjezera chitsimikizo cha sterility ngati kusefera kwa sterilizing kugwiritsidwa ntchito m'malo onse awiri.Zosefera zimayenera kugwiritsidwa ntchito kuchepetsa bioburden ndi particles, zomwe zingatseke zosefera zomaliza msanga.
Zolinga Zopatukana
● Kuseferatu
Chotsani zonyansa za colloidal ndi tinthu tating'ono kuti muwonjezere moyo wautumiki wa zosefera zakutsikira kwa mtsinje
● Sefa yomaliza
Perekani zosefera zosabala zomwe zikugwirizana ndi zomwe zikuchitika pano
Zofunikira pa Ntchito
● Zosefera zomaliza ziyenera kuchotsa mabakiteriya osasintha zotsatira za mankhwala.Chifukwa chake, zoseferazi ziyenera kukhala ndi ma adsorption otsika a mankhwala ophatikizika (API), otsika otsika, osakhala a pyrogenic ndi kukhulupirika kuyesedwa, ndikukhala osabala kapena otsekereza.
● Zosefera zosefera ndi zosefera zomaliza ziyenera kukhala ndi mayendedwe okwanira.Zosefera zomaliza mumakina odzazitsa ziyenera kukhala ndi zida zolimba zoletsa kusinthasintha kwa media panthawi yodzaza ma pulsed flow flow, zomwe zimabweretsa kutulutsidwa kwa tinthu, kudontha kapena zovuta zina.
Malangizo
| Gawo Losefera | Malangizo |
| Kuseferatu | PP |
| Wosatulutsa mpweya | IPF |
| Kusefera komaliza | GALU |
